SP2 - Comparative and integrative computational analysis of distinct and shared genetic, epigenetic, and transcriptomic signatures in SUDsysis

In this SP we are using various databanks to do comparative GWAS meta-analysis and estimation of polygenic risk scores in SUDs and also doing comparative genetic signalling pathway analysis in SUDs.

The scientist are hereby using post-mortem brain tissue from different SUDs to study comparative genome-wide epigenetic and transcriptional alterations and hypothesis-driven analysis in signalling pathways - also on a single cell level.

MArcella Rietschel, phd

Full professor, Wissenschaftliche Direktorin Genetische Epidemiologie in der Psychiatrie, Central institute of mental Health (ZI), Heidelberg University

 

www.zi-mannheim.de

 

Stephanie Witt, PhD

 

PD Dr., Leiterin des molekulargenetischen Labors und der Biobank, Central institute of mental Health (ZI), Heidelberg University

 

www.zi-mannheim.de

 

Anita Hansen, PhD

 

Head of research group, Institute of psychopharmacology, Institute of mental health (ZI), Heidelberg University

www.zi-mannheim.de

 

markus nöthen, PhD

 

Full Professor, Director, Biomedizinisches Zentrum
Universitätsklinikum Bonn (AöR)

www.humangenetics.uni-bonn.de

 

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